Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
The Neuroscience TRC is committed to development of transformational therapeutics for patients with neurodegenerative and neuromuscular diseases. We have built a network of external partnerships across multiple treatment modalities (small molecules, biologics and RNA targeting) that leverage our leadership in protein homeostasis and inflammation to attack neurodegenerative, neuromuscular and neuropsychiatric diseases.
Areas of interest include, but are not limited to, the following approaches:
Disease modifying therapies for neurodegenerative, neuro-inflammatory and neuromuscular diseases; CNS targets that modulate protein homeostasis, protein clearance, inflammation and reduce or eliminate toxic protein production; Neuropsychiatric symptoms associated with neurodegenerative diseases; Emerging technologies (RNA targeting) that when matched to underlying disease genetics can deliver a precision medicine portfolio with a high probability of success to address unmet medical needs; Targets in neuromuscular diseases. Use approaches in cellular, preclinical and translational tools and technologies such as multiomics in tissue and fluid samples to identify novel biomarkers to track drug-target interactions and disease impact.
Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.
Position Summary: The Senior Associate Scientist is a laboratory-based, integral member of the Neuroscience TRC (San Diego site) with a focus on research projects and small and large molecule asset support for a broad range of neurodegenerative indications. The successful applicant will leverage their experience in neuroscience/neuroimmunology and in vitro/ex vivo expertise, working collaboratively with other team members across disciplines to pharmacologically characterize target engagement and pharmacodynamics in CNS-relevant models such as ex vivo tissues, iPSCs/coculture systems and organoids. This position offers great potential for continued growth with exposure to all aspects of disease modelling and drug development and as such, in vivo experience would be considered advantageous. The Senior Associate Scientist will also be in a position to work on project teams across functions and sites and contribute to regulatory submissions.
The desired laboratory skills include cell and protein detection and familiarity with technologies such as flow cytometry, gene expression, various imaging techniques, ELISA and Simple Western. The successful applicant should be comfortable with assay development, troubleshooting experimental procedures and data analysis and proficient in cell culture techniques, including conduct of assays to characterize molecules in iPSC-derived neural cells (mono-, bi- and tri-culture). Good communication skills as well as strong teamwork and team-spirit are required.
Position Responsibilities: In the role as a Senior Associate Scientist within the Neuroscience Preclinical Sciences group, the ideal candidate will be responsible for:
- Implementation and validation of assay systems in relevant cell types to screen and characterize the pharmacological responses to modulation with small and large molecules.
- Development of assays in iPSC/cocultures/organoids with functional readouts that are relevant to the primary neurodegeneration indication and reflective of human genetics or epidemiology.
- Generate, record and report raw data and interpret to refine the next steps.
- Ensuring the proper documentation of all data in electronic notebooks.
- Analysis and presentation of data (eg, Excel and GraphPad Prism), as appropriate and including statistical analysis.
- Presentation of data updates at project team and departmental meetings.
Experience: Basic Qualifications:
- Bachelor's Degree
- 4+ years of academic and / or industry experience
Or
- Master's Degree
- 2+ years of academic and / or industry experience
Preferred Qualifications
- Experience with cell and protein analysis methods including flow cytometry, ELISA and simple western systems is preferred.
- Experience with tissue culture techniques and in particular, iPSC-derived neural cells.
- Experience with human samples (eg, blood) is considered advantageous.
- The candidate must have strong organizational skills and the ability to work well independently as well as in a highly matrixed team-oriented environment.
- Strong written and oral communication skills, with the desire to present scientific findings and data to broader teams.
- Motivated and detail-oriented with a strong interest in driving productivity in clinically directed research.
- Proficiency with Microsoft Excel, PowerPoint, Word, and GraphPad Prism is required.
For CA, based candidates only: The starting compensation for this job is a range from $83,000 - $114,400, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit http://careers.bms.com/life-at-bms/
Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
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