We are seeking a Scientist II who is passionate about developing complex in vitro microphysiological organ-on-chip systems (MPS) and bioprinted models for drug discovery and development. In this role, the scientist will perform hands-on experimentation and provide support to advance the team’s biofabrication efforts.
This position is based on-site in Cambridge, MA, supporting day-to-day laboratory workflows and assisting with model development within a collaborative research environment.
Key Responsibilities
- Support the biofabrication and maintenance of microphysiological systems and bioprinted models.
- Perform routine mammalian cell culture while maintaining a high level of aseptic technique.
- Prepare and handle hydrogels/ECM for use in 3D culture (MPS and bioprinted) platforms.
- Assist in immunofluorescence staining, imaging, and analysis workflows.
- Reconstitute, aliquot, and prepare reagents and media.
- Execute multi-step experimental protocols and workflows.
- Document experimental procedures, observations, and results in electronic lab notebook.
- Assist with inventory management, ordering, and general lab maintenance.
- Support both general and project-specific laboratory operations as project needs evolve.
- Collaborate across different functional teams/locations.
Required Education: High School Diploma or GED required. Bachelor’s Degree or Master’s Degree preferred.(B.S./B.A. in Bioengineering, Biology, Biomedical Engineering, Cell & Molecular Biology, Immunology, or a related field with minimum of 1 year of relevant experience or Master’s Degree)
Required Experience and Skills
- Minimum of 2 years of experience in mammalian cell culture and aseptic technique.
- Experience preparing and handling biomaterials or hydrogels for 3D culture applications.
- Experience working with MPS models, bioprinted platforms, or other 3D cell culture technologies.
- Familiarity with basic microscopy techniques for assessing cell health and experimental progress.
- Strong attention to detail, organizational skills, and accurate documentation practices.
- Demonstrated ability to execute experimental protocols and work with collaborators.
- Ability to work on-site, follow established protocols, and meet deadlines.
- Enthusiastic, self-motivated, and eager to learn new workflows.
Preferred Experience and Skills
- Experience with stem cell culture or differentiation workflows.
- Experience with stem cell-derived organoid models.
- Experience working with MIMETAS organ-on-chip, or similar high throughput, platform.
- Experience working in pharmaceutical drug discovery or development.
- Data analysis experience using Matlab, R, and/or Python.
- Experience with nucleofection.
#eligibleforerp
MSJR
Required Skills:
3D Cell Culture, 3D Cultures, Aseptic Technique, Bioprinting, Bioproduction, Mammalian Cell Culture
