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RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals .
The role offers an opportunity to design and develop critical experiments to answer significant biological questions critical oncology targets and help in creating new RPT therapies for cancer treatments. The ideal candidate will be a highly motivated and technically skilled biologist with excellent interpersonal and communication skills. The role will have an opportunity to work as technical lead on multiple projects ranging from target selection through candidate nomination stages and can be expected to lead early-stage projects in an interdisciplinary setting. The role is highly technical and will need a person who enjoys leading from the bench with strong experimental and data analysis skills and a comfort level in working under tight timelines. The role requires an ability and willingness to work with radioactive isotopes.
Job Responsibilities Essential duties and responsibilities include the following. Other duties may be assigned.
- Conceptualize and execute in vitro assays which contribute to answering key biological questions on project and support the screening, characterization and lead-identification of novel RPT agents .
- Utilize a deep understanding of cancer biology and oncology drug development to support the target selection and initiation of new TRP projects.
- Work in close collaboration with interdisciplinary team members to provide functional biology leadership to guide programs through lead identification/optimization phases.
- Support the overall biology screening and evaluation plan, work closely with chemists, DMPK, imaging and in vivo teams to ensure implementation of screening funnel and appropriate prioritization of experiments.
- Work under the guidance of clinical, translational leads to help implement the translational biology plan to support the clinical development strategy.
- Help generate, review technical reports in support of regulatory submissions and support the publication/presentation plans with active contributions.
- Identify external partners, KOLs, outside expertise that will help advance the pipeline.
- Supervise the work of junior scientists and ensure experimental rigor and high quality.
Education and Experience
- PhD in cancer biology, cell biology, pharmacology, or a related field and a deep understanding of cancer biology and experience working in oncology drug development is ideal.
- 4 + years of experience in pharmaceutical/biotech R&D environments demonstrating successful accomplishments and progressive leadership and broadening responsibilities.
- Experience in working on targeted cancer therapy modalities such as RPTs, ADCs, PDCs is highly desirable.
Skills and Qualifications
- Expertise with invitro, cell-based assay development and optimization and proficiency with Cell culture, molecular biology techniques, ELISA, flow-cytometry, western blot, qPCR, single-cell cloning, immunohistochemistry and related protocols.
- Ability to effectively partner with chemistry/DMPK, imaging and in vivo teams and ability to effectively interpret data and plan experiments accordingly.
- Strong technical problem-solving skills and a basic familiarity with ADME/PK concepts, drug design and the use of appropriate in vivo oncology models is critical.
- Excellent written and oral communication and presentation skills and ability to work in a fast-paced, dynamic, and collaborative environment.
- Ability to work with radioisotopes with strict adherence to radiation safety protocols.
- Demonstrated ability to supervise and effectively guide the work of junior scientists and demonstrated ability of productivity in an industrial drug discovery setting.
Physical Demands While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 20 pounds. Specific vision abilities required by this job include close vision and distance vision.
This is a position that requires working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment with radioactive materials .
Work Environment The noise level in the work environment is usually moderate.
The starting compensation for this job is a range from $127,211-$172,109 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
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